Plant Transcription Factor Database
Previous version: v3.0
Cicer arietinum
WOX Family
Species TF ID Description
XP_004492364.1WOX family protein
XP_004499043.1WOX family protein
XP_004505911.1WOX family protein
XP_012572051.1WOX family protein
XP_004503282.1WOX family protein
XP_004503281.1WOX family protein
XP_004503280.1WOX family protein
XP_004503392.1WOX family protein
XP_004512229.1WOX family protein
XP_004505406.2WOX family protein
XP_012572552.1WOX family protein
XP_004485857.1WOX family protein
XP_004485856.1WOX family protein
XP_012575155.1WOX family protein
XP_004505393.1WOX family protein
XP_012568542.1WOX family protein
XP_004489665.1WOX family protein
XP_012569213.1WOX family protein
XP_012569212.1WOX family protein
XP_004492094.1WOX family protein
XP_004492097.1WOX family protein
XP_004497297.1WOX family protein
XP_004500857.1WOX family protein
XP_004500856.1WOX family protein
XP_012568891.1WOX family protein
WOX Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401

The WOX genes form a plant-specific subclade of the eukaryotic homeobox transcription factor superfamily, which is characterized by the presence of a conserved DNA-binding homeodomain. The analysis of WOX gene expression and function shows that WOX family members fulfill specialized functions in key developmental processes in plants, such as embryonic patterning, stem-cell maintenance and organ formation. These functions can be related to either promotion of cell division activity and/or prevention of premature cell differentiation.

van der Graaff E, Laux T, Rensing SA.
The WUS homeobox-containing (WOX) protein family.
Genome Biol, 2009. 10(12): p. 248.
PMID: 20067590